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The helix located between the two domains of a mip-like peptidyl-prolyl cis-trans isomerase is crucial for its structure, stability,...

FKBP22, a PPIase (peptidyl-prolyl cis-trans isomerase) produced by Escherichia coli, binds FK506 and rapamycin (both immunosuppressive drugs), shares si...
Biswanath,JanaSubrata,Sau  -  《Biochemistry》  -  被引量:  17  -  2013年
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Upper Pleistocene Radiocarbon-Dated Artefacts from the Northern Yukon: Man was in Beringia 27,000 years ago

The evidence presented here indicates that man lived in the eastern part of the Beringian refugium before the peak of the late Wisconsin glaciation (27). He had sharp, stone tools intended for working bone and means of breaking large ...
W N,IrvingC R,Harington  -  《Science》  -  被引量:  6  -  2010年
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Orthogonal analytical approaches to detect potential contaminants in heparin

Heparin is a widely used anticoagulant and antithrombotic agent. Recently, a contaminant, oversulfated chondroitin sulfate (OSCS), was discovered within...
G MarcoZ ZhenqingS Zachary , ... -  《Proceedings of t...  -  被引量:  0  -  2021年

Platinum-Catalyzed, Terminal-Selective C(sp(3))-H Oxidation of Aliphatic Amines

This Communication describes the terminal-selective, Pt-catalyzed C(sp(3))-H oxidation of aliphatic amines without the requirement for directing groups...
L MelissaMS Sanford  -  《Journal of the A...  -  被引量:  0  -  2019年

Decline in pneumococcal nasopharyngeal carriage in children 6-23months with respiratory illnesses following pneumococcal conjugate v...

Following pneumococcal conjugate vaccines (PCVs) implementation, worldwide, pneumococcal carriage rates remained stable, indicating full replacement of ...
K LeoreG DavidGL Noga , ... -  《Vaccine》  -  被引量:  0  -  2021年

Interaction between fast and ultra-slow inactivation in the voltage-gated sodium channel. Does the inactivation gate stabilize the c...

Recently, we reported that mutation A1529D in the domain (D) IV P-loop of the rat skeletal muscle Na(+) channel mu(1) (DIV-A1529D) enhanced entry to an inactivated state from which the channels recovered with an abnormally slow time c...
H KarlheinzS WalterK Oliver , ... -  《Journal of Biolo...  -  被引量:  0  -  2021年

Microenvironment-Responsive Three-Pronged Approach Breaking Traditional Chemotherapy to Target Cancer Stem Cells for Synergistic Ino...

Three-pronged nanoparticles (NPs) that can efficiently prohibit the proliferation of large tumor are developed for inoperable large tumor therapy. The N...
L YanZ RuilongL Zhiguo , ... -  《Small》  -  被引量:  0  -  2018年

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